This 4 day course provides a comprehensive overview of data analysis for metabolic profiling studies, using data acquired from both liquid chromatography-mass spectrometry and NMR spectroscopy. The course is taught by expert practitioners who have developed many of the approaches used, and takes place at one of the world’s leading research centres for metabolic profiling. Participants will come away with an understanding of data analysis tools and approaches which they will be able to implement in their own laboratories.
The course combines lectures and tutorial sessions to ensure a thorough understanding of both theoretical and practical applications. Throughout there will be an emphasis on understanding concepts rather than detailed mathematical derivations. No prior training in metabolic profiling or chemometrics is required.

Day 1: Introductory lectures and tutorials regarding the pre-processing of data acquired via MS and NMR.
Day 2: Lectures and tutorials to introduce basic chemometrics tools such as PCA and a look ahead to new technologies.
Day 3: Lectures and tutorials regarding the supervised and advanced chemometrics techniques e.g. PLS, OPLS and O2PLS, including tips and tricks for practical application.
Day 4: Using pathway based tools to interpret results and application of statistical tools to metabolite identification, e.g. STOCSY.

Online booking: http://www5.imperial.ac.uk/medicine/coursebookings/handsondata_11_2014.html

Please visit our website at http://www1.imperial.ac.uk/iiptc/, contact Dr Tim Ebbels (t.ebbels@imperial.ac.uk) or Dr Elizabeth Want on 0207 594 3023 (iptc@imperial.ac.uk) for further information.