The Early-career Members Network (EMN) invites you to the Webinar series featuring:

Learning From Repository-Scale Untargeted Metabolomics Data

Speaker: Dr. Wout Bittremieux (University of Antwerp, Belgium)

This presentation will showcase how untargeted metabolomics data often face the challenge of limited annotation, with only a minority of mass spectra confidently identified using spectral libraries. Dr. Wout Bittremieux will present a transformative data-driven approach that has led to the creation of a propagated spectral library, known as the “suspect” spectral library, derived from repository-wide molecular networking results on the GNPS platform. Through the reanalysis of over 500 million mass spectra in 1335 publicly available datasets, the group compiled a novel spectral library consisting of 87,916 new reference spectra that are structurally related to known reference molecules. Dr. Bittremieux will demonstrate how the suspect library enables the discovery of novel molecules, effectively doubling the annotation rate on average. This advancement provides a powerful tool for researchers to explore previously inaccessible molecular landscapes, fostering novel biological insights.

An active voice in the computational mass spectrometry community, Dr. Bittremieux has published extensively in top-tier scientific journals and is a key member of the European Bioinformatics Community for Mass Spectrometry (EuBIC-MS). He leads the CompMS interest group of the International Society for Computational Biology (ISCB) and has been instrumental in developing mass spectrometry data standards through the Proteomics Standards Initiative (PSI).

Click here to learn more about this latest webinar by Dr. Wout Bittremieux.