Time:   7:00 a.m.–8:00 a.m. US Eastern Standard Time (1:00 p.m.–2:00 p.m. Central European Time)

Speakers:
Dr. Stacey Reinke, Edith Cowan University, Australia
Dr. Craig Wheelock, Karolinska Institutet, Sweden

Abstract:
There are multiple inherent challenges in performing large-scale non-targeted metabolomics. These include a diverse array of issues ranging from managing multiple clinical collection sites, accounting for unbalanced study design, developing analytical platforms with high precision across large sample numbers, creating the necessary data analysis workflows, and interpreting the eventual results with clinical collaborators. In this presentation, we will provide an overview of the pan-European U-BIOPRED project (Unbiased Biomarkers for the Prediction of Respiratory Disease Outcomes), which brought together over 40 academic and industry partners as well as patient organizations to identify molecular sub-phenotypes of severe asthma.