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DTSTART;TZID=UTC:20140906T000000
DTEND;TZID=UTC:20140906T235959
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CREATED:20231115T204352Z
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SUMMARY:The 1st Unified Workshop on Proteome and Metabolome Informatics
DESCRIPTION:8am registration\, 9am – 6pm workshop @ ECCB 2014 \nWorkshop website: http://www.cadetbioinformatics.org/workshops/eccb14/ \nSummary \nAt present there is little contact between metabolomics and proteomics fields at both wet and dry-lab levels\, and so key synergies are being lost. A number of packages offer the complete quantification and identification workflow for discovery proteomics and metabolomics but there is little cross-fertilisation between metabolome and proteome informatics groups\, despite numerous overlaps and similarities between disciplines. In some ways this is because metabolome and proteome informatics research has originated from different fields (broadly chemometrics and genome bioinformatics\, respectively)\, yet their distinct perspectives have been applied to identical or similar problems. \nThe integration of quantitative outputs from proteomics and metabolomics for dynamic systems and pathway modelling is reliant on appropriate and accurate statistical handling. Since metabolomics and proteomics data are processed differently\, their statistical integration is a significant challenge – there are differing assumptions on biological variation; differing transformations and error distributions from the various processing steps; and subtly different corrections for multiple hypothesis testing. Cross-fertilisation and cross-development of methodology and ideas between disciplines has the prospect of seeding novel and effective new approaches of analysis. \nWe therefore believe there is a timely opportunity to bring together the informatics communities in metabolomics and proteomics: \n\nTo underpin existing and to drive new cross-disciplinary collaborations in order to facilitate better statistical integration and therefore better downstream modelling and ultimately biological understanding.\nTo allow these disciplines to better ‘borrow strength’ from each other\, improving quantitative workflows at all levels.\nTo impact on researcher mobility due to clearer understanding of the commonality and subtle differences in workflows between disciplines.\nTo support development of joint data exchange and reporting standards for optimal integration of omics data.\n\nTarget Audience \nThis workshop will be of interest to all researchers in proteomics or metabolomics\, whether at the wet-lab or informatics level. It will also be of relevance to systems modellers and network biologists who integrate proteomics and metabolomics data and who wish to gain a greater understanding of how upstream processing of this data is performed. \nThe core aim for this workshop is for there to be an equal proportion of talks on proteome and metabolome informatics. In particular\, we will prefer talks that already describe some synergy between the two fields. Speakers are advised to ensure metabolomics concepts are accessible to a proteomics audience\, and vice versa. \nCall for Contributions \nThe abstract submission form is here. \nAbstract submission deadline: July 7th\, 2014. \nNotification of acceptance: July 21st\, 2014. \nSubmissions for presentation or poster are invited. \nLocation \nFORUM building\nFaculté de Médecine\n4\, rue Kirschleger\nStrasbourg \nConfirmed Speakers \nTheodore Alexandrov\, University of Bremen / University of California San Diego / SCiLS\nConrad Bessant\, Queen Mary University of London\, UK\nRick Dunn\, University of Birmingham\, UK\nHenning Hermjakob\, European Bioinformatics Institute\, UK\nSimon Hubbard\, University of Manchester\, UK\nAndy Jones\, University of Liverpool\, UK\nOliver Kohlbacher\, University of Tübingen\, Germany\nLennart Martens\, Universiteit Gent\, Belgium\nJeffrey Morris\, MD Anderson Cancer Center\, TX\, USA\nMichael Gerlich (Steffen Neumann Lab)\, IPB Leibniz Institute of Plant Biochemistry\, Halle\, Germany\nChristoph Steinbeck\, European Bioinformatics Institute\, UK \nOrganising Committee \nDr Andrew Dowsey\, CADET\, University of Manchester\nDr Simon Rogers\, School of Computer Science\, University of Glasgow\nProf Rainer Breitling\, MIB\, University of Manchester\nDr Richard Unwin\, CADET\, University of Manchester
URL:https://metabolomicssociety.org/event/the-1st-unified-workshop-on-proteome-and-metabolome-informatics/
LOCATION:ECCB\, Strasbourg\, France\, ECCB\, Strasbourg\, France\, Strasbourg\, France
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