Dr. Caroline Johnson is an Assistant Professor of Epidemiology and Metabolomics in the Department of Environmental Health Sciences at Yale School of Public Health (YSPH). In 2009, she graduated from Imperial College London with a PhD in Analytical Chemistry under the mentorship of Profs. Jeremy Nicholson, John Lindon and Ian Wilson, where she studied the role of reactive drug metabolites in relation to toxicity. She then held a postdoctoral appointment at the National Cancer Institute, NIH, in Dr. Frank Gonzalez’s lab and examined the biological effects of ionizing radiation and dietary exposures on human health using metabolomics. From 2012-2016 she directed the cancer metabolism efforts at the Scripps Research Center for Metabolomics with Prof. Gary Siuzdak’s lab where she was involved in the optimization of XCMS Online and METLIN technologies.
Since joining YSPH in 2016, her lab’s primary focus has been to develop metabolomics for epidemiologic and population-level analysis. The lab is also using mass spectrometry imaging approaches to better understand tissue metabolite heterogeneity and the link between metabolites and cellular pathology. The lab is currently investigating the relationship between genetic and environmental influences in women with colon cancer, and the examination of early-life exposures in pregnancy outcomes. Dr. Johnson also serves on the editorial boards for Metabolites, Toxicological Sciences and Frontiers in Immunology and Nutrition.