Andrew Lane

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I graduated with a BSC and a PhD from the Department of Biochemistry, University College London and then carried out postdoctoral research first in biophysical chemistry with Kasper Kirschner at the Biozentrum, Basel and then as an EMBO Fellow at Stanford Magnetic Resonance Laboratory with Oleg Jardetzky. My background in enzymology, biophysics and structural biology lead to subsequent applications especially using NMR with stable isotope tracers to understanding metabolic networks, particular in cancer. I have been using NMR in metabolic analyses since the early 1980's, in parallel with biophysical studies of proteins and nucleic acids. I have been collaborating with Teresa Fan and Richard Higashi for more than 30 years, and we established methods for stable isotope tracing in a wide variety of model systems as well as human subjects, that we termed SIRM (for Stable Isotope Resolved Metabolomics).